Dr. Elisha Fredman
Radiation Oncologist / Patient-Centered Radiotherapy
Dr. Elisha Fredman is a US board-certified Radiation Oncologist with 10 years of academic and clinical experience in the treatment of prostate, kidney, and bladder cancers.
About:
Currently the co-Director of Genitourinary Radiation Therapy and Director of Research at the Davidoff Cancer Center, Dr. Fredman previously served as the Medical Director of Radiation Oncology in Cleveland, Ohio at the University Hospitals Geauga Medical Center. He lectures internationally on the topic of Prostate Radiation, has been awarded more than half a million USD in research grants and support, serves on the editorial board of 5 medical journals focused on radiation oncology, and has authored over 50 clinical publications.
Dr. Fredman helped pioneer Boston Scientific’s SpaceOAR™ procedure and is Boston Scientific’s sole educational clinical liaison for the procedure across Europe, the Middle East, and Asia. This groundbreaking and quick procedure separates the rectum from the prostate before a patient undergoes radiation therapy, using an FDA-approved hydrogel injection, that is shown in clinical studies to protect the patient’s urinary, bowel, and sexual function and improve patient outcomes.
In this elegant outpatient procedure (under partial or local anesthesia), the patient’s rectum is gently moved away from the radiation field. Dr. Fredman simultaneously inserts gold markers into the prostate to increase the accuracy and precision of the subsequent radiotherapy.
More than 500,000 patients have been treated with SpaceOAR™ in over 500 medical institutions globally, growing 400% since 2020. According to Boston Scientific, more than half of US prostate cancer patients undergoing radiotherapy receive the SpaceOAR™ procedure beforehand.
On behalf of Boston Scientific, Dr. Fredman trains physicians and nurses to safely administer the SpaceOAR™ procedure.
SpaceOAR™ Clinical Quick Facts:
More about SpaceOAR™ from Boston Scientific:
Dr. Fredman’s Areas of Expertise:
- SpaceOAR™ Hydrogel procedure
- Cancers of the prostate, kidney, bladder, testes, ureters
- Stereotactic ablative radiotherapy (SBRT/SABR)
- Palliative radiotherapy
Education and Experience:
- Dual degree in Neuroscience and Psychology – Brandeis University
- Doctor of Medicine (MD) – Case Western Reserve University School of Medicine
- Internship in Internal Medicine – MetroHealth Hospital
- Residency in Radiation Oncology – Seidman Cancer Center, Cleveland Medical Center
- Chief Resident in Radiation Oncology – Seidman Cancer Center
- Medical Director of Radiation Oncology – Geauga Medical Center
- Associate Professor – Case Western Reserve University School of Medicine
- Disease team leader for Genitourinary Radiation Oncology – Davidoff Cancer Center
- Head of research and innovation in Radiation Oncology – Davidoff Cancer Center
Selected Publications:
Zhang Y, Yu H, Xu M, Han F, Tian C, Kim S, Fredman E, Zhang J, Benedict-Alderfer C, Zheng QY. Pathological features in the lmna(dhe/+) mutant mouse provide a novel model of human otitis media and laminopathies. Am J Pathol. 2012; 181(3):761-74. PMID: 22819531.
Semaan MT, Fredman ET, Shah JR, Fares SA, Murray GS, Megerian CA. Surgical duration of cochlear implantation in an academic university-based practice. Am J Otolaryngol. 2013; 34(5):382-387. PMID: 23415572.
Kumar AM, Fredman ET, Coppa C, El-Gazzaz G, Aucejo FN, Abdel-Wahab M. Patterns of cancer recurrence in localized resected hepatocellular carcinoma. Hepatobiliary Pancreat Dis Int. 2015; 14(3):269-75. PMID: 26063027.
Fredman E, Kumar A, El-Gazzaz G, Aucejo F, Coppa C, Abdel-Wahab M. Predicting close local failure after liver resection for hepatocellular carcinoma. Applied Radiation Oncology. 2015; 4(1):14-21.
Russo S, Steele S, Fredman E, Biswas T. Current topics in the multimodality treatment of locally advanced rectal cancer. Future Oncol. 2016; 12(7):963-79. PMID: 26880222.
Fredman E, Mansur DB, Russo S. The evolving role of radiation therapy in pediatric Hodgkin’s disease. Expert Rev Anticancer Ther. 2016; 16(6):605-13. PMID: 27137877.
Fredman E, Abdel-Wahab M, Kumar A. Influence of treatment technique on outcome and toxicity in anal cancer. J Radiat Oncol. 2017; 6(4):413-21. PMID: 29213359.
Fredman E, Traughber B, Podder T, Colussi V, Zheng Y, Russo S, Herrmann K, Paspulati R, Waggoner S, Zanotti K, Nagel C, Nakayama J, Machtay M, Ellis R. 3T multi-parametric MRI-guided high dose rate combined intracavitary and interstitial adaptive brachytherapy for the treatment of cervical cancer with a novel split-ring applicator. Brachytherapy. 2017; 17(2):334-44. PMID: 29097137.
Fredman E, Traughber B, Gross A, Podder T, Colussi V, Vinkler R, Machtay M, Ellis R. Comparison of multiparametric MRI-based and transrectal ultrasound-based preplans with intraoperative ultrasound-based planning for low dose rate interstitial prostate seed implantation. J Appl Clin Med Phys. 2019; 20(6):31-38. PMID: 31004396.
Xu Z, Traughber B, Fredman E, Albani D, Ellis R, Podder T. Appropriate Methodology for EBRT and HDR Intracavitary/Interstitial Brachytherapy Dose Composite and Clinical Plan Evaluation for Patients With Cervical Cancer. Pract Radiat Oncol. 2019; 9(6):559-71. PMID: 31238167.
Baydoun A, Xu K, Heo JU, Yang H, Zhou F, Bethell LA, Fredman E, Ellis RJ, Podder TK, Traughber MS, Paspulati RM, Pengjiang Q, Traughber BJ, Muzic RF. Synthetic CT Generation of the Pelvis in Patients with Cervical Cancer: A Single Input Approach Using Generative Adversarial Network. IEEE Access. 2021; 9:17208-21. PMID: 33747682.
Baydoun A, Xu K, Bethell LA, Zhou F, Heo JU, Zhao K, Fredman E, Ellis RJ, Pengjiang Q, Muzic RF, Traughber BJ. Auto-Contouring FDG-PET/MR Images for Cervical Cancer Radiation Therapy: An Intelligent Sequential Approach Using Focally Trained, Shallow U-Nets. Intell Based Med. 2021; 5:100026.
Fredman ET, Guo G, Spratt DE. Importance of radiotherapy to the primary in metastatic hormone sensitive prostate cancer. Prostate Cancer Prostatic Dis. 2021; (4):929-930. PMID: 33833377.
Yuan J, Fredman E, Jin J, Choi S, Mansur D, Sloan A, Machtay M, Zheng Y. Monte Carlo Dose Calculation Using MRI Based Synthetic CT Generated by Fully Convolutional Neural Network for Gamma Knife Radiosurgery. Technol Cancer Research Treatment. 2021; 20:15330338211046433. PMID: 34632872.
Fredman E, Traughber B, Kharouta M, Podder T, Lo S, Ponsky L, MacLennan G, Paspulati R, Ellis B, Machtay M, Ellis R. Focal Prostate Stereotactic Body Radiation Therapy With Correlative Pathological and Radiographic-Based Treatment Planning. Front Oncol. 2021; 11:744130. PMID: 34604088.
Gross A, Yuan J, Spratt D, Fredman E. Case Series: Role of an iodinated rectal hydrogel spacer, SpaceOAR™ VueTM, in the context of low-dose-rate brachytherapy, for enhanced post-operative contouring to aid in accurate implant evaluation and dosimetry. Front Oncol. 2021; 11:810955. PMID: 35004333.
Fredman E, Kharouta M, Dorth J, Patel M, Padula G, Yao M. Dehydration Reduction In Head & Neck Cancer: DRIHNC trial: Daily oral fluid and electrolyte maintenance to prevent Acute Care Clinic and Emergency Department visits for patients receiving radiation for Head & Neck and esophageal cancer. Adv Radiat Oncol. 2022; 7(6): 101026.
Kundel Y, Kurman N, Sulimani O, Gavrielli S, Nachalon Y, Moore A, Kashtan H, Fenig E, Brenner B, Popovtzer A, Fredman E. The effect of gastric fundus radiation dose on postoperative anastomotic leakage in esophageal cancer. Front Oncol. 2023; 13:1080089. PMID: 36925923.
Fredman E, Weinstock-Sabah M, Icht O, Moore A, Shochet T, Limon D, Bragilovski D. Same day versus delayed simulation imaging after placement of a perirectal hydrogel spacer for prostate radiotherapy. Front Oncol. 2023; 13:1236113.
Fredman E, Icht O, Moore A, Bragilovski D, Kindler Y, Golan S, Limon D. SABR-Dual: A phase II/III trial of two-fraction versus five-fraction stereotactic radiotherapy for localized low- and favorable intermediate-risk prostate cancer. BMC Cancer. 2024;24(1):431. doi: 10.1186/s12885-024-12165-1.
Icht O, Schlosser S, Weinstock-Sabbah M, Rephael M, Bragilovski D, Moore A, Shochet T, Limon D, Fredman E. The role of a radiopaque peri-rectal hydrogel spacer in aiding accurate daily image-guidance for prostate radiotherapy. Front Oncol. 2024. Under Review.
Millot J, Arenas-Gallo C, Silver E, Goldman M, Picciotto S, Jia AY, Zaorsky NG, Spratt DE, Fredman E, et al. Major Complications and Adverse Events Related to Use of SpaceOAR™ Hydrogel for Prostate Cancer Radiotherapy. Urology. 2024:S0090-4295(24)00142-0. doi: 10.1016/j.urology.2023.12.034.
Podder TK, Fredman ET, Ellis RJ. Advances in Radiotherapy for Prostate Cancer Treatment, In: Schatten H. (eds.) Molecular & Diagnostic Imaging in Prostate Cancer. Advances in Experimental Medicine and Biology, vol 1096, New York, NY: Springer, Cham, 2018, 31-47.
Request an Appointment / More Information:
Your message has been sent
Radiation Oncology / Patient-centered Radiotherapy 